TOBI LAB DOCUMENTATION

Welcome to the official GitHub organization of the TOBI Lab, led by Prof. Katleen De Preter. We are part of the VIB-UGent Center for Medical Biotechnology (CMB) and affiliated with VIB.AI. Below you can find a list of pipelines and repositories we have developed, and on the subsequent pages are documentation and links to downloads and source code (hosted on Github).

Projects

BismarkPipeline

Methylation (Bisulfite-Sequencing) analysis pipeline of cfRRBS samples using Bismark.

DecoNFlow pipeline

DecoNFlow is a bioinformatics analysis pipeline used for computational deconvolution of DNA methylation data. It allows deconvolution of samples using both reference-based and reference-free deconvolution tools.

MethylSeq pipeline (TOBI lab version)

Methylation (Bisulfite-Sequencing) analysis pipeline using Bismark or bwa-meth + MethylDackel.

SillyMix pipeline

Sillymix is a bioinformatics analysis pipeline used to perform in-silico mixtures of tumoral and healthy fastq files at specified sequencing depth (in number of reads) and tumoral fractions.